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Table 2 Baseline characteristics of a meta-analysis study of D-dimer in the diagnosis of periprosthetic infection

From: The accuracy of D-dimer in the diagnosis of periprosthetic infections: a systematic review and meta-analysis

Author

Year

Country

Type of research

Sample size

Case group/control group

Average age

Male/female

Gold Standard

Sampling type

Threshold

Whether to exclude inflammatory diseases

Whether to set a control group

Prosthesis type

Typology of infection

Wang [21]

2020

China

Retrospective

157

51/106

64.6

70/87

MSIS

Serum

1220 ng/ml

Yes

Yes

NA

Chronic

Qin [22]

2019

China

Forward-looking

122

55/67

65.9

53/69

ICM

Serum

1170 ng/ml

Yes

Yes

NA

Chronic

Pannu [14]

2020

USA

Retrospective

111

89/22

70

62/49

ICM

Serum

850 ng/ml

No

Yes

NA

NA

Hu [23]

2020

China

Retrospective

77

40/37

60.8

37/40

MSIS

Serum

955 ng/ml

No

Yes

NA

NA

Shahi [12]

2017

USA

Forward-looking

195

86/109

59.7

101/94

ICM

Serum

850 ng/ml

No

Yes

NA

NA

Fu [19]

2019

China

Forward-looking

30

15/15

65.6

9/21

MSIS

Plasma

850 ng/ml

Yes

Yes

NA

NA

Li [13]

2019

China

Retrospective

565

95/470

NA

248/317

ICM

Plasma

1250 ng/ml

No

Yes

NA

NA

Huang [20]

2019

China

Retrospective

101

31/70

64.9

NA

ICM

Serum

850 ng/ml

Yes

Yes

NA

NA

Xiong [15]

2019

China

Forwardlooking

80

26/54

65.4

54/26

MSIS

Serum

756 ng/ml

Yes

Yes

NA

NA

Xu [24]

2019

China

Retrospective

318

129/189

NA

NA

ICM

Plasma

1020 ng/ml FEU

Yes

Yes

NA

NA

  1. The control group was the aseptic loosening group. NA = not applicable