Globulin and albumin to globulin ratio precisely diagnose periprosthetic joint infection and determine the timing of second-stage reimplantation

Table 6 Plasma levels of all markers in patients with successfully controlled infection

Markers	Normal range	Pre-resection	Pre-reimplantation	P value
CRP (mg/L)	< 5.00	31.67 ± 36.76	3.40 ± 6.96	< 0.001
ESR (mm/h)	< 30.00	43.97 ± 25.19	10.82 ± 6.53	< 0.001
PLT (× 10⁹/L)	125–350	282.22 ± 71.56	221.53 ± 51.75	< 0.001
MPV (fL)	7.4–11.0	9.67 ± 0.73	10.06 ± 0.65	0.001
PCT (%)	0.09–0.30	0.27 ± 0.07	0.22 ± 0.05	< 0.001
PMR	–	29.47 ± 8.37	22.16 ± 5.60	< 0.001
GLB (g/L)	20–40	33.32 ± 5.70	27.73 ± 3.65	< 0.001
AGR	1.2–2.4	1.05 ± 0.19	1.41 ± 0.21	< 0.001
PLT/AGR	–	280.21 ± 160.48	161.39 ± 46.23	< 0.001

Wilcoxon’s signed-rank test for paired samples (n = 42)
PJI, periprosthetic joint infection; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; PLT, platelet; MPV, mean platelet volume; PCT, plateletcrit; PMR, PLT to MPV ratio; GLB, globulin; AGR, albumin to globulin ratio

ISSN: 1749-799X