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Table 4 Combinational diagnostic value of the markers for PJI

From: Globulin and albumin to globulin ratio precisely diagnose periprosthetic joint infection and determine the timing of second-stage reimplantation

Markers

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

PLT combined with inflammatory markers

 PLT and ESR

51.9

55.9

46.1

67.5

 PLT or ESR

94.9

90.6

84.3

96.6

 PLT and CRP

62.0

63.0

51.0

72.7

 PLT or CRP

87.3

92.1

87.3

92.1

PCT combined with inflammatory markers

 PCT and ESR

63.3

57.5

48.1

71.6

 PCT or ESR

93.7

91.3

87.1

95.9

 PCT and CRP

64.6

52.0

45.5

70.2

 PCT or CRP

87.3

90.3

82.1

91.8

PMR combined with inflammatory markers

 PMR and ESR

55.7

59.1

45.8

62.5

 PMR or ESR

94.9

90.6

86.2

96.6

 PMR and CRP

59.5

65.4

51.6

72.2

 PMR or CRP

86.1

92.9

88.3

91.5

  1. PJI, periprosthetic joint infection; CI, confidence interval; AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; PLT, platelet; PCT, plateletcrit; PMR, PLT to MPV ratio; MPV, mean platelet volume