Diagnostic accuracy of calprotectin in periprosthetic joint infection: a diagnostic meta-analysis

Table 1 Characteristics of the studies in meta-analysis for the diagnosis of PJI applying calprotectin

Study	Year	Country	Study design	Gender(M/F)	Median age*	Joint type	Detection method	Cutoff values	Gold standard
Bakker et al. [17]	2017	Netherlands	P	NA	NA	Hip/knee/shoulder	LFA	50 mg/L	MSIS
Bakker et al. [16]	2017	Netherlands	P	25/36	65/60	Hip/knee/shoulder/elbow	LFA	50 mg/L	MSIS
Salari et al. [13]	2019	Italy	P	36/40	69	Knee	ELISA	50 mg/L	ICM
Trotter et al. [14]	2020	UK	R	37/32	74.3	Hip/knee	LFA	50 mg/L	ICM/ICM-cr
Zhang et al. [18]	2020	China	P	21/42	64/57	Hip/knee	ELISA	173 ug/ml	MSIS
Grzelecki et al. [12]	2020	Poland	P	25/60	65.5/68.3	Hip/knee	ELISA	1.0 mg/L or 1.5 mg/L	ICM
Warren et al. [15]	2021	USA	P	57/66	66.9/65.4	Knee	ELISA/ LFA	50 mg/L	MSIS

*The values were given as the number with PJI/non-PJI
P prospective study, R retrospective study, LFA lateral flow assay, NA not applicable

ISSN: 1749-799X