Association between serum estradiol level, sex hormone binding globulin level, and bone mineral density in middle-aged postmenopausal women

Table 4 Association between sex hormone binding globulin level (nmol/L) and lumbar bone mineral density (mg/cm²)

	Model 1 β (95% CI)	Model 2 β (95% CI)	Model 3 β (95% CI)
Sex hormone binding globulin	− 0.05 (− 0.34, 0.23)	− 0.13 (− 0.41, 0.14)	0.01 (− 0.30, 0.31)
Sex hormone binding globulin categories
Q1	Reference	Reference	Reference
Q2	− 13.36 (− 47.43, 20.71)	− 9.25 (− 42.62, 24.12)	− 15.19 (− 49.77, 19.40)
Q3	− 48.66 (− 81.85, − 15.48)	− 47.00 (− 79.39, − 14.62)	− 42.37 (− 76.34, − 8.41)
Q4	− 20.17 (− 51.88, 11.54)	− 24.51 (− 55.61, 6.60)	− 13.86 (− 49.23, 21.51)
P for trend	0.094	0.039	0.260

Model 1: no covariates were adjusted. Model 2: age, and race were adjusted. Model 3: age, race, educational level, body mass index, ratio of family income to poverty, moderate activities, smoked at least 100 cigarettes in life, had at least 12 alcohol drinks in a year, blood urea nitrogen, serum uric acid, serum phosphorus, and serum calcium were adjusted
*P < 0.05; **P < 0.01; ***P < 0.001

ISSN: 1749-799X