Association of MIR17HG and MIR155HG gene variants with steroid-induced osteonecrosis of the femoral head in the population of northern China

Table 4 The subgroup information of the MIR17HG gene and MIR155HG gene

Subgroup	SNP	Alleles	MAF		HWE-p^a	ORs	95% CI		p^b
Subgroup	SNP	A/B	Case	Control	HWE-p^a	ORs	95% CI		p^b
Age,> 45	rs77218221	C/T	0.1	0.052	0.467	2.03	1.02	4.04	0.041
Gender, male	rs11911469	A/C	0.164	0.113	1.000	1.53	1.02	2.3	0.040
	rs34904192	A/G	0.19	0.259	0.312	0.67	0.47	0.96	0.030
Gender, female	rs11911469	A/C	0.1	0.19	0.282	0.50	0.26	0.94	0.029
Course, months	rs4143370	C/G	0.187	0.11	0.186	1.86	1.04	3.32	0.035
Case, > 25	rs77218221	C/T	0.097	0.038	1.000	2.73	1.16	6.40	0.017
Control, ≤ 25	rs34904192	A/G	0.291	0.193	0.783	1.72	1.06	2.78	0.027

SNP, single-nucleotide polymorphism; HWE, Hardy–Weinberg’s equilibrium; OR, odds ratio; 95% CI, 95% confidence interval; MAF, minor allele frequency
^ap values were calculated by exact test
^bp values were calculated by Pearson’s chi-squared test

ISSN: 1749-799X