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Table 3 Univariate and multivariable analysis of factors associated with DFS and OS

From: Overexpression of KIAA1199, a novel strong hyaluronidase, is a poor prognostic factor in patients with osteosarcoma

Parameter

DFS n = 36

OS n = 49

P value

  

P value

Univariate analysis*

    

 Gender (male/female)

0.137

  

0.623

 Age (60 ≦/< 60 years)

0.747

  

0.945

 Size (8 ≦/< 8 cm)

0.706

  

0.107

 Location (pelvis/others)

0.685

  

0.018

 Histology (osteoblastic/others)

0.524

  

0.511

 Metastasis (present/absent)

―

  

0.007

 Necrosis rate (90 ≦/< 90%)

0.495

  

0.458

 KIAA1199 positivity (high/low)

0.054

  

0.026

 HABP positivity (high/low)

0.275

  

0.029

Multivariable analysisâ™±

 

HR

95% CI

P value

 Location (pelvis/others)

―

39.99

5.16-358.96

0.001

 Metastasis (present/absent)

―

15.98

3.38-101.47

< 0.001

 KIAA1199 positivity (high/low)

―

5.08

1.10-51.65

0.036

 HABP positivity (high/low)

―

8.62

2.08-52.13

0.002

  1. *Log-rank test, ♱Cox regression model with Firth’s correction method