Table 2 Mankin scoring criteria
From: T-614 attenuates knee osteoarthritis via regulating Wnt/β-catenin signaling pathway
Structure | Standard | Score |
|---|---|---|
Structure | Normal | 0 |
Surface irregularities | 1 | |
Pannus and surface irregularities | 2 | |
Clefts to transitional zone | 3 | |
Clefts to radial zone | 4 | |
Clefts to calcified zone | 5 | |
Complete disorganizations | 6 | |
Cells | Normal | 0 |
Diffuse hypercellularity | 1 | |
Cloning | 2 | |
Hypocellularity | 3 | |
Safranin-O staining | Normal | 0 |
Slight reduction | 1 | |
Moderate reduction | 2 | |
Severe reduction | 3 | |
No dye noted | 4 | |
Tidemark integrity | Intact | 0 |
Crossed by blood vessels | 1 |