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Table 2 Mankin scoring criteria

From: T-614 attenuates knee osteoarthritis via regulating Wnt/β-catenin signaling pathway

Structure Standard Score
Structure Normal 0
Surface irregularities 1
Pannus and surface irregularities 2
Clefts to transitional zone 3
Clefts to radial zone 4
Clefts to calcified zone 5
Complete disorganizations 6
Cells Normal 0
Diffuse hypercellularity 1
Cloning 2
Hypocellularity 3
Safranin-O staining Normal 0
Slight reduction 1
Moderate reduction 2
Severe reduction 3
No dye noted 4
Tidemark integrity Intact 0
Crossed by blood vessels 1