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Table 1 Characteristics of the included studies

From: The efficacy and safety of tranexamic acid in high tibial osteotomy: a systematic review and meta-analysis

Author

Year

Study type

Operation

TXA route

TXA group

Control group

Sample

Age

Intervention

Sample

Age

Intervention

Chen

2020

RCS

HTO

IV&Topical

52

58.3 ± 10.4

TXA

48

56.6 ± 10.2

None

Kim

2018

RCS

HTO

IV

75

55.0 ± 6.8

TXA

75

55.7 ± 5.5

None

Ni

2020

PCS

HTO

IV

50

52.5 ± 2.8

TXA

50

52.9 ± 3.1

Normal saline

Palanisamy

2018

RCS

HTO

IV

66

58 ± 5

TXA

86

57 ± 6

None

Suh

2018

RCS

HTO

Topical

15

60 ± 5.6

TXA

15

56 ± 5.7

None

  1. PCS prospective comparison study, RCS retrospective comparison study, HTO high tibial osteotomy, IV intravenous, TXA tranexamic acid