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Table 1 Characteristics of the included studies

From: The efficacy and safety of tranexamic acid in high tibial osteotomy: a systematic review and meta-analysis

Author Year Study type Operation TXA route TXA group Control group
Sample Age Intervention Sample Age Intervention
Chen 2020 RCS HTO IV&Topical 52 58.3 ± 10.4 TXA 48 56.6 ± 10.2 None
Kim 2018 RCS HTO IV 75 55.0 ± 6.8 TXA 75 55.7 ± 5.5 None
Ni 2020 PCS HTO IV 50 52.5 ± 2.8 TXA 50 52.9 ± 3.1 Normal saline
Palanisamy 2018 RCS HTO IV 66 58 ± 5 TXA 86 57 ± 6 None
Suh 2018 RCS HTO Topical 15 60 ± 5.6 TXA 15 56 ± 5.7 None
  1. PCS prospective comparison study, RCS retrospective comparison study, HTO high tibial osteotomy, IV intravenous, TXA tranexamic acid