Skip to main content

Table 8 Evaluation of the top 10 downregulated DEGs of the protein-protein interaction network by MNC centrality, MCC centrality, and degree centrality

From: Bioinformatics analysis and identification of genes and molecular pathways in steroid-induced osteonecrosis of the femoral head

Rank

MNC centrality

MCC centrality

Degree centrality

1

MKRN1

FBXL4

MAPK1

2

FBXL4

MKRN1

FBXL4

3

GABARAPL2

MAPK1

AKT2

4

MAP1LC3B

SIAH2

MKRN1

5

SIAH2

UBE2H

FOXO3

6

UBE2H

AKT2

DCUN1D1

7

AKT2

FOXO3

GABARAPL2

8

MAPK1

GABARAPL2

MAP1LC3B

9

FOXO3

MAP1LC3B

SIAH2

10

ANKRD9

DCUN1D1

UBE2H