Fig. 1

Upregulated RANKL and NFATC1 expressions in the synovial tissues of RA patients compared with that of OA patients. The expressions of RANKL and NFATC1 in synovial tissues from RA patients and OA patients were analyzed by immunohistochemistry, RT-PCR, and western blot. Data are representative images or expressed as the mean ± SD of each group from 3 separate patients. a Representative immunohistochemistry images (magnification ×400) (n = 3). b RT-PCR analysis of RANKL and NFATC1 mRNA levels (n = 3). c Western blot detection of RANKL and NFATC1 (n = 3). *p < 0.05 vs the OA group