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Table 1 Outline of procedures and evaluations conducted in each evaluation moment. Days are counted from treatment day

From: RETRACTED ARTICLE: Effect of a single intra-articular high molecular weight hyaluronan in a naturally occurring canine osteoarthritis model: a randomized controlled trial

Modality

Evaluation moment

0 Treatment day

8

15

30

90

180

Treatment

X

     

Functional assessment

 Stance analysis

X

X

X

X

X

X

 Pedometer

X

X

X

X

X

X

 Goniometry

X

X

X

X

X

X

 Thigh girth measurement

X

X

X

X

X

X

Imaging

 Digital Thermography

X

X

X

X

X

X

 Digital radiography

X

  

X

X

X

Clinical Metrology Instruments

 HVAS

X

X

X

X

X

X

 CBPI

X

X

X

X

X

X

 COI

X

X

X

X

X

X

 LOAD

X

X

X

X

X

X

Laboratorial evaluation

 SF CRP

X

X

 

X

X

X

 SF IL-1

X

X

 

X

X

X

  1. CBPI, Canine Brief Pain Inventory; COI, Canine Orthopedic Index; CRP, C-reactive protein; HVAS, Hudson Visual Analogue Scale; IL-1, interleukin 1; LOAD, Liverpool Osteoarthritis in Dogs; SF, synovial fluid