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Table 1 Outline of procedures and evaluations conducted in each evaluation moment. Days are counted from treatment day

From: Effect of a single intra-articular high molecular weight hyaluronan in a naturally occurring canine osteoarthritis model: a randomized controlled trial

Modality Evaluation moment
0 Treatment day 8 15 30 90 180
Treatment X      
Functional assessment
 Stance analysis X X X X X X
 Pedometer X X X X X X
 Goniometry X X X X X X
 Thigh girth measurement X X X X X X
Imaging
 Digital Thermography X X X X X X
 Digital radiography X    X X X
Clinical Metrology Instruments
 HVAS X X X X X X
 CBPI X X X X X X
 COI X X X X X X
 LOAD X X X X X X
Laboratorial evaluation
 SF CRP X X   X X X
 SF IL-1 X X   X X X
  1. CBPI, Canine Brief Pain Inventory; COI, Canine Orthopedic Index; CRP, C-reactive protein; HVAS, Hudson Visual Analogue Scale; IL-1, interleukin 1; LOAD, Liverpool Osteoarthritis in Dogs; SF, synovial fluid