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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Circ_0116061 regulated the proliferation, apoptosis, and inflammation of osteoarthritis chondrocytes through regulating the miR-200b-3p/SMURF2 axis

Fig. 3

Circ_0116061 sponged miR-200b-3p. a The binding sites between miR-200b-3p and circ_0116061 were shown. Dual-luciferase reporter assay (b) and biotin-labeled RNA pull-down assay (c) were performed to measure the interaction between miR-200b-3p and circ_0116061. d After transfecting with si-NC or si-circ_0116061 into OA chondrocytes, the expression of miR-200b-3p was detected by qRT-PCR. e Pearson correlation analysis was used to analyze the correlation between miR-200b-3p and circ_0116061 in OA cartilage tissues. ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X