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Table 4 Comparison of gene expression patterns of DEGs participated in inflammation

From: Deer antler extract potentially facilitates xiphoid cartilage growth and regeneration and prevents inflammatory susceptibility by regulating multiple functional genes

Gene name

Expression level (FPKM)

log2 fold change (DAE/blank)

p value

Blank

DAE

40S ribosomal protein S24 (Rps24)

4192.80

2010.43

−1.06

0

Fatty acid-binding protein (Fabp4)

2432.08

468.50

−2.38

0

Beta-2-microglobulin (B2m)

516.35

237.92

−1.12

0

Osteoglycin (Ogn)

140.89

67.67

−1.06

2.91E−46

Retinoid-binding protein 7 (Rbp7)

253.48

65.29

−1.96

4.24E−116

Lysozyme C-1 (Lyz1)

120.53

55.53

−1.12

6.30E−56

Adiponectin (Adipoq)

293.37

45.45

−2.69

0

CCAAT/enhancer-binding protein delta (Cebpd)

80.67

38.92

−1.05

5.26E−32

Thyroid hormone-inducible hepatic protein (Thrsp)

221.82

36.82

−2.59

0

DnaJ homolog subfamily C member 15 (Dnajc15)

70.79

34.30

−1.05

2.10E−18

CCAAT/enhancer-binding protein beta (Cebpb)

70.21

32.67

−1.10

5.94E−40

Platelet glycoprotein 4 (Cd36)

112.80

27.68

−2.03

4.07E−293

Resistin (Retn)

144.77

25.36

−2.51

2.83E−84

Collagen alpha-1(IV) chain (Col4a1)

43.97

18.93

−1.22

3.28E−137

Angiotensinogen (Agt)

63.79

18.67

−1.77

9.28E−99

O-acetyl-ADP-ribose deacetylase MACROD1 (Fragment) (Macrod1)

38.50

16.56

−1.22

6.04E−18

Interferon alpha-inducible protein 27-like protein 2B (Ifi27l2b)

46.39

16.54

−1.49

8.20E−11

NF-kappa-B inhibitor alpha (Nfkbia)

38.08

16.10

−1.24

8.49E−29

Complement C1q subcomponent subunit C (C1qc)

29.82

14.74

−1.02

2.57E−11

CCAAT/enhancer-binding protein alpha (Cebpa)

39.76

12.49

−1.67

2.30E−79

Stromal cell-derived factor 1 (Cxcl12)

23.58

11.21

−1.07

2.72E−21

C-C motif chemokine 21a (Ccl21a)

64.52

9.09

−2.83

6.67E−71

C-X-C motif chemokine 13 (Cxcl13)

30.87

8.38

−1.88

1.49E−28

Sorting nexin-2 (Snx2)

15.47

6.35

−1.28

5.23E−17

Cathepsin S (Ctss)

12.32

5.89

−1.06

3.23E−07

Complement C1q subcomponent subunit B (C1qb)

13.93

5.73

−1.28

1.13E−08

Matrix metalloproteinase-23 (Mmp23)

15.41

5.72

−1.43

1.68E−12

Spondin-2 (Spon2)

13.07

5.71

−1.19

2.15E−11

Leucine-rich alpha-2-glycoprotein (Lrg1)

12.31

5.55

−1.15

7.57E−08

Peroxidasin homolog (Pxdn)

12.59

5.36

−1.23

3.23E−41