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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: The effect of the WKYMVm peptide on promoting mBMSC secretion of exosomes to induce M2 macrophage polarization through the FPR2 pathway

Fig. 3

WKYMVm peptide downregulated the expression of TFEB in mBMSC by combination with FPR2 pathway. mBMSCs incubated with WKYMVm peptide (1 μmol/L) or WKYMVm peptide (1 μmol/L) plus WRW4 peptide (10 μmol/L) for 24 h. a Western blotting carried out with TFEB and β-actin special antibodies to determine the TFEB protein expression level. b qRT-PCR was used to analyze the relative RNA expression of TFEB. Data represent means ± SD. *P < .05, **P < .01, and ***P < .001 relative to controls in which the concentration of WKYMVm peptide was 0 μmol/L

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