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Table 4 Top 10 genes with the highest centrality degree in the PPI network. Centrality degree was calculated by the CentiScaPe plug-in, and one cluster was identified by MCODE analysis with threshold k-core = 5

From: Integrated traditional Chinese medicine alleviates sciatica while regulating gene expression in peripheral blood

Gene

Degree

MCODE_cluster

TLR4

26

Clustered

MMP9

22

Clustered

MPO

20

Unclustered

CAMP

18

Clustered

RETN

18

Clustered

TLR5

17

Unclustered

CEACAM8

16

Clustered

CD86

16

Unclustered

LCN2

15

Clustered

IL1RN

13

Clustered

  1. TLR4 toll-like receptor 4, MMP9 matrix metallopeptidase 9, MPO myeloperoxidase, CAMP cathelicidin antimicrobial peptide, RETN resistin, TLR5 toll-like receptor 5, CEACAM8 CEA cell adhesion molecule 8, CD86 CD86 molecule, LCN2 lipocalin 2, IL1RN interleukin 1 receptor antagonist
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X