Skip to main content

Table 3 Univariate analysis of factors for periprosthetic infection

From: Surgical drainage after limb salvage surgery and endoprosthetic reconstruction: is 30 mL/day critical?

Variable

Group or measure

Non-infected

(n = 264)

Infected

(n = 31)

P value

Age (years)

Mean

42

35

0.11 a

Resection length (cm)

Mean

17

20

0.05 a

Gender

Male

135

25

0.002 b

Female

129

6

Pathology

Benign

14

0

0.38 b

Sarcoma

170

25

0.08 b

Metastasis

80

6

0.30 b

Site

Proximal femur

85

12

0.73 b

Distal femur

118

13

Proximal tibia

50

4

Total femur

11

2

Surgeon

A

92

11

0.42 b

B

66

8

C

30

3

Others

76

9

Preoperative chemotherapy

Yes

160

26

0.001 b

No

104

5

Postoperative chemotherapy

Yes

85

22

0.01 b

No

170

4

Both pre- and postoperative chemotherapy

Yes

127

25

0.001 b

No

137

6

Any chemotherapy

Yes

180

26

0.10 b

No

84

5

Preoperative radiotherapy

Yes

35

3

0.78 b

No

229

28

Postoperative radiotherapy

Yes

24

2

1.00 b

No

240

29

Number of drains

1

178

16

0.06 b

≥ 2

86

15

Duration of drains (days)

Mean

8.1

10.0

0.04 a

Total drainage (mL)

Mean

1,332

2,138

0.007 a

Rate of drainage (mL/day)

Mean

167

198

0.07 a

Last drainagec (mL/day)

Mean

73

70

0.86 a

Last drainagec (mL/day)

≤ 30

78

10

0.84 b

> 30

186

21

Last drainagec (mL/day)

≤ 60

138

14

0.57 b

> 60

126

17

Last drainagec (mL/day)

≤ 120

214

27

0.62 b

> 120

50

4

Duration of surgery (hours)

Mean

5.2

6.2

0.05 a

Re-dose antibiotics in surgery

Yes

64

14

0.03 b

No

143

12

Estimated blood loss (mL)

Mean

759

1,176

0.09 a

  1. aStudent’s t test
  2. bPearson’s chi-square test or Fisher’s exact test
  3. cLast day of drainage prior to drain removal