Effect of denosumab switched from bisphosphonates in preventing joint destruction in postmenopausal rheumatoid arthritis patients with anti-cyclic citrullinated peptide antibodies

Table 4 Comparison of the changes of bone mineral density and radiographic vertebral fractures at 12 months

Variable	Bisphosphonate group (n = 50)	Denosumab group (n = 56)	p value
BMD
Lumbar spine (g/cm²)	0.034 (0.083)	0.033 (0.072)	0.32
Femoral neck (g/cm²)	0.0045 (0.033)	0.021 (0.042)	0.011*
Total hip (g/cm²)	0.0042 (0.056)	0.027 (0.062)	0.012*
Vertebral fracture, n (%)	2 (4)	1 (1.8)	0.49

ISSN: 1749-799X