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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Silencing of Vangl2 attenuates the inflammation promoted by Wnt5a via MAPK and NF-κB pathway in chondrocytes

Fig. 3

Knockdown of Vangl2 attenuated IL-1β-induced inflammatory activation in ATDC5. a, b The knockdown efficiency of siRNA targeting Vangl2 was detected by Western blotting (a) and RT-qPCR (b). c Effects of Vangl2 inhibition on MMP3, MMP9, MMP13, and IL-6 mRNA levels were measured by RT-qPCR. d Western blotting for MMP3, MMP9, MMP13, and IL-6 in three groups. Densitometric quantification values were normalized for GAPDH. **P < 0.01, ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X