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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Mesenchymal stem cell-originated exosomal lncRNA HAND2-AS1 impairs rheumatoid arthritis fibroblast-like synoviocyte activation through miR-143-3p/TNFAIP3/NF-κB pathway

Fig. 1

HAND2-AS1 upregulation inhibits tumor-like biologic behaviors of RA-FLSs via NF-κB pathway. a qRT-PCR analysis of HAND2-AS1 expression in RA synovial tissues and normal synovial tissues. b–h MH7A cells were transfected with HAND2-AS1 or vector. b qRT-PCR analysis of HAND2-AS1 expression in cells. c CCK-8 assay of cell proliferation. d Flow cytometric analysis of cell apoptosis. e Wound healing assay of cell migration. f Transwell assay of cell invasion. g Detection of IL-6 and TNF-α levels in cells with ELISA. h Western blot analysis of the level of p-p65 and p65. *P < 0.05, **P < 0.001, ***P < 0.0001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X