Table 2 Trend of drug resistance rate of S. aureus in orthopedics from 2012 to 2017
Antibiotics | Drug resistance rate [%(strains/strains)] | Value | ||||||
|---|---|---|---|---|---|---|---|---|
2012 | 2013 | 2014 | 2015 | 2016 | 2017 | χ2 | p | |
Penicillin | 100.0 (20/20) | 100.0 (16/16) | 100.0 (20/20) | 90.9 (20/22) | 100.0 (20/20) | 100.0 (14/14) | --- | --- |
Oxacillin | 50.0 (12/24) | 39.1 (9/23) | 53.1 (17/32) | 50.0 (13/26) | 60.9 (14/23) | 75.0 (12/16) | 5.632 | 0.344 |
Amoxicillin-clavulanic acid | 20.0 (4/20) | 37.5 (6/16) | 59.1 (13/22) | 60.9 (14/23) | 66.7 (12/18) | 50.0 (8/16) | 12.006 | 0.035 |
Ceftriaxone | … | 50.0 (8/16) | 52.4 (11/21) | 47.8 (11/23) | 73.7 (14/19) | 75.0 (12/16) | 5.488 | 0.241 |
Levofloxacin | 25.0 (6/24) | 18.2 (4/22) | 21.9 (7/32) | 14.8 (4/27) | 25.0 (6/24) | 25.0 (4/16) | 1.330 | 0.932 |
Tetracycline | 53.8 (14/26) | 27.3 (6/22) | 42.3 (11/26) | 11.5 (3/26) | 25.0 (6/24) | 37.5 (6/16) | 12.740 | 0.026 |
Ciprofloxacin | 33.3 (8/24) | 18.2 (4/22) | 33.3 (11/33) | 14.8 (4/27) | 25.0 (6/24) | 25.0 (4/16) | 4.104 | 0.535 |
Gentamicin | 41.2 (12/26) | 20.0 (4/20) | 25.0 (8/32) | 16.7 (4/26) | 45.8 (11/24) | 37.5 (6/16) | 10.161 | 0.071 |
Cotrimoxazole | 21.4 (6/28) | 16.0 (4/25) | 12.1 (4/33) | 11.1 (3/27) | 8.3 (2/24) | 12.5 (2/16) | 2.270 | 0.829 |
Ampicillin | 100.0 (20/20) | 100.0 (17/17) | 100.0 (23/23) | 100.0 (21/21) | 100.0 (20/20) | 100.0 (12/12) | --- | --- |
Erythromycin | 83.3 (20/24) | 50.0 (11/22) | 75.0 (24/32) | 76.9 (20/26) | 66.7 (16/24) | 75.0 (12/16) | 7.076 | 0.211 |
Nitrofurantoin | 0.0 (0/14) | 0.0 (0/6) | 0.0 (0/6) | 0.0 (0/5) | 0.0 (0/6) | 0.0 (0/7) | --- | --- |
Linezolid | 0.0 (0/26) | 0.0 (0/22) | 0.0 (0/30) | 0.0 (0/25) | 0.0 (0/24) | 0.0 (0/16) | --- | --- |
Vancomycin | 0.0 (0/12) | 0.0 (0/22) | 0.0 (0/26) | 0.0 (0/26) | 0.0 (0/24) | 0.0 (0/16) | --- | --- |