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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Elevated expression of MMP8 and MMP9 contributes to diabetic osteoarthritis progression in a rat model

Fig. 4

The effect of MMP8 and MMP9 on the apoptosis of chondrocytes in the knee joint of diabetes-induced OA rats. a IHC showing the effects of MMP8/MMP9 overexpression and inhibition on the expression of BCL2 in knee joint cartilage. b Image-Pro Plus software was used for the quantitative analysis of BCL2. c TUNEL assay results showing the effect of overexpression and inhibition of MMP8 and MMP9 on the number of apoptotic cells. d Quantitative analysis of the number of apoptotic cells. *p < 0.05; **p < 0.01

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