Fig. 2
From: High expression of ABCG2 is associated with chemotherapy resistance of osteosarcoma
Effect of knockdown of ABCG2 on the sensitivity of OS cell lines to DOX. a, b ABCG2 mRNA expression in OS cell lines was effectively knocked down by lentivirus as evidenced by qPCR and WB analysis. c Knockdown of ABCG2 could reverse the resistance of OS cells to DOX. The CCK-8 assay showed that the DOX-resistant HOS cells and DOX-resistant U2OS cells transfected with ShABCG2 were more sensitive to the DOX treatment than those transfected with ShCtrl