Fig. 1
From: High expression of ABCG2 is associated with chemotherapy resistance of osteosarcoma
Upregulated expression of ABCG2 in DOX-resistant OS cells. a Successful establishment of DOX-resistant OS cell lines was verified by CCK8 assay. Cell viability of DOX-treated HOS cells and U2OS cells was remarkably higher than those not treated by DOX. b Through qPCR, we confirmed that mRNA expression level of ABCG2 was significantly increased in DOX-resistant cell lines as compared with normal cell lines