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Table 4 Univariate and multivariate logistic regression analysis for patients with osteosarcoma by lung metastasis

From: Risk factors for lung metastasis at presentation with malignant primary osseous neoplasms: a population-based study

CharacteristicUnivariate analysisMultivariate analysis
OR (95% CI)POR (95% CI)P
Age
 < 30Reference NI 
> 300.821 (0.608–1.108)0.197  
Race
 WhiteReference NI 
 Black1.142 (0.779–1.673)0.497  
 Other11.043 (0.636–1.711)0.867  
 Unknown1.083 (0.126–9.328)0.942  
Gender
 MaleReference Reference 
 Female1.410 (1.057–1.881)0.0191.267 (0.945–1.698)0.114
Primary site
 ExtremityReference   
 Axial0.862 (0.623–1.192)0.368NI 
Grade
 Low gradeReference Reference 
 High grade5.769 (2.328–14.296)0.0004.861 (1.948–12.131)0.001
 Unknown5.381 (2.106–13.751)0.0004.326 (1.681–11.136)0.002
Tumor size
 < 5Reference Reference 
> 54.107 (2.064–8.171)0.0003.432 (1.715–6.867)< 0.001
 Unknown6.281 (2.969–13.288)0.0005.470 (2.568–11.654)< 0.001
  1. OR odds ratio, CI confidence interval, NI not included. n = 1457
  2. 1Including American Indian/Alaska Native, Asian/Pacific Islander