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Table 4 Univariate and multivariate logistic regression analysis for patients with osteosarcoma by lung metastasis

From: Risk factors for lung metastasis at presentation with malignant primary osseous neoplasms: a population-based study

Characteristic

Univariate analysis

Multivariate analysis

OR (95% CI)

P

OR (95% CI)

P

Age

 < 30

Reference

 

NI

 

> 30

0.821 (0.608–1.108)

0.197

  

Race

 White

Reference

 

NI

 

 Black

1.142 (0.779–1.673)

0.497

  

 Other1

1.043 (0.636–1.711)

0.867

  

 Unknown

1.083 (0.126–9.328)

0.942

  

Gender

 Male

Reference

 

Reference

 

 Female

1.410 (1.057–1.881)

0.019

1.267 (0.945–1.698)

0.114

Primary site

 Extremity

Reference

   

 Axial

0.862 (0.623–1.192)

0.368

NI

 

Grade

 Low grade

Reference

 

Reference

 

 High grade

5.769 (2.328–14.296)

0.000

4.861 (1.948–12.131)

0.001

 Unknown

5.381 (2.106–13.751)

0.000

4.326 (1.681–11.136)

0.002

Tumor size

 < 5

Reference

 

Reference

 

> 5

4.107 (2.064–8.171)

0.000

3.432 (1.715–6.867)

< 0.001

 Unknown

6.281 (2.969–13.288)

0.000

5.470 (2.568–11.654)

< 0.001

  1. OR odds ratio, CI confidence interval, NI not included. n = 1457
  2. 1Including American Indian/Alaska Native, Asian/Pacific Islander