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Table 3 Analysis of the association between SNPs of RETN gene and steroid-induced ONFH risk

From: Variants in RETN gene are associated with steroid-induced osteonecrosis of the femoral head risk among Han Chinese people

SNP IDModelGenotypeControlCaseOR (95% CI)p value
rs34861192CodominantGG1301461 
AG61520.76(0.49–1.18)0.220
AA910.10(0.01–0.79)0.029*
DominantGG1301461 
AG-AA70530.67(0.44–1.03)0.071
RecessiveGG-AG1911981 
AA910.11(0.01–0.85)0.035*
Log-additive0.63(0.43–0.93)0.019*
rs3219175CodominantGG1291461 
AG62500.71(0.46–1.11)0.133
AA910.10(0.01–0.79)0.029*
DominantGG1291461 
AG-AA71510.63(0.41–0.98)0.038*
RecessiveGG-AG1911961 
AA910.11(0.01–0.86)0.036*
Log-additive0.60(0.41–0.88)0.010*
rs3745368CodominantGG1371561 
 AG56410.64(0.40–1.02)0.059
AA620.29(0.06–1.45)0.131
DominantGG1371561 
AG-AA62430.61(0.38–0.95)0.030*
RecessiveGG-AG1931971 
AA620.32(0.06–1.63)0.170
Log-additive0.61(0.41–0.92)0.019*
rs1477341CodominantTT51681 
AT105900.64(0.41–1.02)0.059
AA43320.56(0.31–1.00)0.051
DominantTT51681 
AT-AA1481220.62(0.40–0.96)0.030*
RecessiveTT-AT1561581 
AA43320.74(0.44–1.23)0.239
Log-additive0.73(0.55–0.98)0.036*
  1. SNP single-nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
  2. p value adjusted for age was calculated by logistic regression
  3. Italicized values are statistically significant
  4. *p < 0.05 indicates statistical significance