Angiotensin II blockade had no effect on range of motion after total knee arthroplasty: a retrospective review

Table 1 Demographic and preoperative characteristics

	ACEIs (N = 35)	ARBs (N = 19)	Controls (N = 87)	p value
Male, %	19	6	27	0.048^a
Age, years; mean ± SD	63.6 ± 7.9	66.4 ± 7.8	61.5 ± 10.0	1.710^b
Comorbidities
BMI, kg/m²	33.7 ± 6.7	31.1 ± 6.5	30.4 ± 6.7	0.050^c
Diabetes, N	10	6	5	< 0.001^a
Opioids, N	17	5	31	0.226
Statin, N	18	10	21	0.004^a
Preoperative ROM, degrees; mean ± SD
Flexion	107.7 ± 13.7	108.9 ± 11.6	111.0 ± 12.3	0.423^b
Extension	3.1 ± 3.8	2.4 ± 4.5	2.3 ± 3.9	0.366^b
Total arc	104.6 ± 15.9	106.5 ± 13.3	108.7 ± 13.8	0.317^b
Manipulation under anesthesia	2	1	5	1.000^d

SD standard deviation, BMI Body mass index, ROM Range of motion
Demographic data for study patients analyzed. ^aχ², ^bKruskal, ^cANOVA, ^dFisher exact

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