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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Nerve growth factor-chondroitin sulfate/hydroxyapatite-coating composite implant induces early osseointegration and nerve regeneration of peri-implant tissues in Beagle dogs

Fig. 6

The implantation of NGF-CS/HA-coating implants markedly upregulated the levels of NGF-, osteogenesis differentiation-, and neurogenic differentiation-related genes. RT-qPCR analysis of Trk A and p75 (a, b); OCN and Runx-2 (c, d); and Nestin, NF, and tubulin β4 (eg) in HA- and NGF-CS/HA-coating implant groups at 2, 4, and 8 weeks. *P < 0.05. Two dogs with 16 implant teeth (8 teeth for HA coating and 8 teeth for NGF-CS/HA coating) at each time point

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