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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Nerve growth factor-chondroitin sulfate/hydroxyapatite-coating composite implant induces early osseointegration and nerve regeneration of peri-implant tissues in Beagle dogs

Fig. 5

NGF-CS/HA-coating implants induced the growth of nerve fibers in the peri-implant tissues. a The number of nerve fiber was confirmed via DiI neural tracer in HA- and NGF-CS/HA-coating implant groups at 2, 4, and 8 weeks. Magnification, × 100; scale bar = 200 μm. b The expression of NF200 was monitored using IHC assay in HA- and NGF-CS/HA-coating implant groups at 2, 4, and 8 weeks. Magnification, × 400; scale bar = 100 μm. The arrows denote the longitudinal section of the nerve fibers. Two dogs with 16 implant teeth (8 teeth for HA coating and 8 teeth for NGF-CS/HA coating) at each time point

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