Fig. 7
From: Effect of alendronate on the femoral metaphyseal defect under carbamazepine in ovariectomized rats
Immunohistochemical staining of osteocalcin (OCN), collagen I (Col I), and tartrate-resistant acid phosphatase (Tracp-5b) were used to observe osteogenesis in femur distal defects a Deptor expression of CON and OVX rats evaluated by IHC (N = 20). The red dotted rectangles indicate positive areas while solid rectangles refer to a higher magnification of immunoreactivity positive areas. Magnification was × 200. Scale bars 200 μm. b Immunohistochemistry quantitative analyses for OCN, Col I, and Tracp-5b in the bone defects among the 4 groups. Data are expressed as mean ± SD. *P < 0.05, **P < 0.01