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Table 2 Results of multivariate meta-regression analyses for demographic (mean age and gender) and clinical variables (doses of MSCs and OA grade) to predict effects of MSCs on the VAS score

From: Efficacy of mesenchymal stromal cells for the treatment of knee osteoarthritis: a meta-analysis of randomized controlled trials

Covariate

Coefficient

95%CI

t value

P value

Age

0.4879

− 0.3639, 1.3398

1.19

0.248

Gender

0.4929

− 0.3598, 1.3457

1.20

0.244

Grade of osteoarthritis

0.5032

− 0.3489, 1.3555

1.22

0.234

Duration of disease

0.5177

− 0.3416, 1.3769

1.25

0.225

Dose of MSCs

0.4893

− 0.3635, 1.3421

1.19

0.247

  1. Abbreviations: MSCs mesenchymal stem cells, OA osteoarthritis