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Table 2 Results of multivariate meta-regression analyses for demographic (mean age and gender) and clinical variables (doses of MSCs and OA grade) to predict effects of MSCs on the VAS score

From: Efficacy of mesenchymal stromal cells for the treatment of knee osteoarthritis: a meta-analysis of randomized controlled trials

Covariate Coefficient 95%CI t value P value
Age 0.4879 − 0.3639, 1.3398 1.19 0.248
Gender 0.4929 − 0.3598, 1.3457 1.20 0.244
Grade of osteoarthritis 0.5032 − 0.3489, 1.3555 1.22 0.234
Duration of disease 0.5177 − 0.3416, 1.3769 1.25 0.225
Dose of MSCs 0.4893 − 0.3635, 1.3421 1.19 0.247
  1. Abbreviations: MSCs mesenchymal stem cells, OA osteoarthritis