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Table 1 Characteristics of included studies

From: Fibrinogen performs better than D-dimer for the diagnosis of periprosthetic joint infection: a meta-analysis of diagnostic trials

Study

Country

Study design

Gender (F/M)

Age (years ± SD)

Involved joints (PJI/total)

Sites of arthroplasty

Disease spectrum

Comorbidities *

Cutoff

D-dimer

Qin et al. [11]

China

P

69/53

65.21 ± 10.51

55/122

Hips and knees

Chronic PJI + aseptic

Excluded

1170 ng/ml

Xiong et al. [13]

China

P

48/32

61.60 ± 12.22

26/80

Hips and knees

PJI + aseptic

Excluded

756 ng/ml

Shahi et al. [12]

USA

P

94/101

62.46

57/195

Hips and knees

Primary arthroplasty + PJI + aseptic + reimplantation

Not excluded

850 ng/mL

Xu et al. [14]

China

R

NM

NM

82/224

Hips and knees

PJI + aseptic

Excluded

1020 ng/mL

Huang et al. [8]

China

R

46/34

67.15 ± 2.64

31/101

Hips and knees

Primary arthroplasty + PJI + aseptic

Excluded

850 ng/mL

Pannu et al. [10]

USA

R

62/49

68.89 ± 10

49/111

Hips and knees

PJI + aseptic

NM

2300 ng/mL

Hu et al. [7]

China

R

41/36

63.08

40/77

Hips and knees, 2 others

PJI + aseptic

Not excluded

955 ng/ml

Li et al. [15]

China

R

NM

NM

76/439

Hips and knees

PJI + aseptic

Excluded

1250 ng/ml

Wu et al. [17]

China

R

82/54

66.32 ± 11.73

35/116

Hips and knees

PJI + aseptic+reimplantation

Not excluded

410 ng/ml

Fibrinogen

Li et al. [15]

China

R

NM

NM

76/439

Hips and knees

PJI + aseptic

Excluded

4.01 g/L

Wu et al. [17]

China

R

82/54

66.32 ± 11.73

35/116

Hips and knees

PJI + aseptic+reimplantation

Not excluded

3.61 g/L

Klim et al. [16]

Austria

P

NM

65.50 ± 15.31

78/124

Hips and knees

PJI + aseptic

Excluded

5.19 g/L

Xu et al. [9]

China

R

NM

NM

153/360

Hips and knees

PJI + aseptic

Excluded

3.57 g/L

  1. NM not mentioned, PJI periprosthetic joint infection, P perspective, R retrospective
  2. *Comorbidities referred to comorbidities influencing D-dimer or fibrinogen