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Table 2 Quality of evidence according to the GRADE criteria

From: Pin vs plate fixation for metacarpal fractures: a meta-analysis

Outcomes

Number of studies (design); no. of participants

Effect size (95% CI)

Characteristics of the included studies

 

Risk of biasa

Inconsistency

Indirectnessb

Imprecisionc

Publication bias

Overall GRADE quality score

Disabilities of the arm, shoulder, and hand score (DASH)

6 (5 observational; 1 RCT); n = 329

WMD − 0.77 (− 3.55, 2.00)

Serious

Not serious

Serious

Not serious

Undetected

Low

Range of movement (ROM) at the meta-carpo-phalangeal joint

7 (6 observational; 1 RCT); n = 359

WMD 4.44 (− 4.19, 13.07)

Serious

Not serious

Serious

Not serious

Undetected

Low

Grip strength

4 (4 observational); n = 205

WMD − 4.63 (− 14.52, 5.26)

Serious

Not serious

Serious

Seriousc

Undetected

Very low

Limb shortening (in mm) on radiography

4 (4 observational); n = 219

WMD 1.25 (0.03, 2.47)

Serious

Not serious

Serious

Serious c

Undetected

Very low

Visual analogue score (VAS)

2 (2 observational); n = 107

WMD − 0.01 (− 0.27, 0.26)

Serious

Not serious

Serious

Seriousc

Undetected

Very low

Complication rates

8 (7 observational; 1 RCT); n = 439

RR 0.93 (0.57, 1.53)

Serious

Not serious

Serious

Not serious

Undetected

Low

  1. aMajority of the studies included were observational in design
  2. bStudies were done in different geographic settings. Further, studies differed in the age of the participants and the duration of follow-up post-operatively
  3. cCriteria for optimal information size (OIS) not met and the 95% CI overlap no effect and includes important benefit and harm