MiR-455-3p downregulation facilitates cell proliferation and invasion and predicts poor prognosis of osteosarcoma

Table 1 Relationship between miR-455-3p expression and the clinical characteristics of the OS patients

Features	Total no. n = 105	miR-455-3p expression		P values
Features	Total no. n = 105	Low (n = 53)	High (n = 52)	P values
Age (years)
≤ 20	62	30	32	0.607
> 20	43	23	20	0.607
Gender
Female	46	24	22	0.759
Male	59	29	30	0.759
Tumor size (cm)
≤ 8	62	26	36	0.036
> 8	43	27	16	0.036
Differentiation				0.168
Well/moderate	70	32	38
Poor	35	21	14
Distant metastasis
Negative	87	40	47	0.043
Positive	18	13	5	0.043
Tumor site
Distal femur	51	27	24	0.823
Proximal tibia	36	18	18
others	18	8	10
Clinical stage
IA-IIA	61	24	37	0.007
IIB-III	44	29	15	0.007

ISSN: 1749-799X