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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: The role of antibiotic-loaded bone cement in complicated knee arthroplasty: relevance of gentamicin allergy and benefit from revision surgery — a case control follow-up study and algorithmic approach

Fig. 2

Algorithmic interdisciplinary approach to complicated TKAs with suspected allergic or adverse reactions. Following an inconclusive work-up for commonplace problem elicitors, symptomatic TKA-bearers should be sent for patch testing, particularly in cases of atopic diathesis or positive family history of allergy. After ruling out other systemic disorders, epicutaneous testing for relevant metal implant or bone cement hypersensitivities is carried out. This is typically accompanied by lymphocyte transformation testing for systemic sensitization and, in cases of earlier revisions or arthroscopic debridements, histopathological assessment (R/O, rule out; BPO, benzyl peroxide; MMA, methylmethacrylate; DMPT, N,N-dimethyl-p-toluidine; HQ, hydroquinone)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X