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Table 1 Characteristics of the studies in meta-analysis for the diagnosis of PJI applying D-dimer

From: Diagnostic accuracy of D-dimer in periprosthetic joint infection: a diagnostic meta-analysis

Study

Year

Country

Study design

Gender (M/F)

Median age*

BMI*

Detection method

Cutoff values

Gold standard

Pannu et al. [21]

2020

USA

R

62/49

68/70

30.5/30.5

NA

850 ng/ml

ICM

Hu et al. [12]

2020

China

R

37/40

65.57/60.78

NA

Immunoturbidimetric assay

0.955 μg/ml

MSIS

Xu et al. [24]

2019

China

R

NA

NA

NA

NA

1.02 mg/L FEU

MSIS

Xiong et al. [23]

2019

China

P

54/26

59.76/65.42

22.87/25.07

Immunoturbidimetric assay

756 ng/ml

MSIS

Qin et al. [22]

2019

China

P

53/69

64.66/65.89

23.84/22.12

NA

1170 ng/ml

MSIS

Li et al. [17]

2019

China

R

470/95

61.3/63.7

25.15/25.01

STA-R Evolution analyzer

1.25 mg/ml

ICM

Shahi et al. [18]

2017

USA

P

101/94

NA

NA

NA

850 ng/ml

MSIS

Fu et al. [19]

2019

China

P

9/21

65.47/65.60

24.67/25.72

NA

850 ng/ml

MSIS

Huang et al. [20]

2019

China

R

NA

69.27/64.94

NA

NA

850 ng/ml

MSIS

  1. *The values were given as the number with non-PJI/PJI
  2. P prospective study, R retrospective study, NA not applicable