Fig. 7
From: BM-MSCs differentiated to chondrocytes for treatment of full-thickness cartilage defect of the knee
MRI post-surgery. Patient SPC: a sagittal fat-supressed proton density-weighted image 3 months after treatment. The graft tissue homogeneous filling the defect. Subchondral marrow edema. b Coronal fat-suppressed proton density-weighted image 3 months after treatment. Graft tissue homogeneous filling the defect. There is subchondral bone marrow edema, C: Sagittal fat-suppressed proton density-weighted image 53 months after treatment. The repair site is now filled with a congruent articular surface. Normal signal of the cartilage. Persistent bone marrow. d Coronal fat-suppressed proton density-weighted image 53 months after treatment. The repair site is now filled with a congruent articular surface. Persistent bone marrow edema and a focal irregularity in superficial layer are present. Patient CRC: e Sagittal fat-suppressed proton density-weighted image 6 months after the index procedure. The graft tissue inhomogeneous fills the defect with overgrowth of repair cartilage. Subtle subchondral marrow edema. f Coronal fat-suppressed proton density-weighted image 6 months after treatment. There is graft tissue in homogeneously filling the defect with overgrowth of the repaired cartilage. Subtle subchondral marrow edema. g Sagittal fat-suppressed proton density-weighted image 15 months after treatment. The repair site shows evidence of progression of tissue incorporation and a congruent articular surface. There is no bone marrow edema. h Coronal fat-suppressed proton density-weighted image 15 months after treatment. The repair site is now filled with incorporated tissue, and a congruent articular surface is evident. There is no bone marrow edema