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Table 5 Subgroup analysis results

From: Meta-analysis of serum and/or plasma D-dimer in the diagnosis of periprosthetic joint infection

Subgroup analyses

No. of papers

No. of patients

Sen

Spe

PLR

NLR

DOR

SROC (SE)

Overall studies

7

1285

0.75 (0.70–0.79)

0.69 (0.66–0.72)

3.01 (1.84–4.93)

0.32 (0.19–0.53)

10.2 (3.63–28.64)

0.8288 (0.0525)

Type of blood sample

 Plasma

3

787

0.67 (0.60–0.73)

0.60 (0.56–0.64)

1.59 (1.28–1.99)

0.59 (0.48–0.72)

2.69 (1.92–3.77)

0.6599 (0.0261)

 Serum

4

498

0.86 (0.80–0.91)

0.84 (0.80–0.88)

4.91 (2.85–8.48)

0.19 (0.09–0.37)

28.25 (9.60–83.15)

0.9096 (0.0332)

  1. Sen sensitivity, Spe specificity, PLR positive likelihood ratio, NLR negative likelihood ratio, DOR diagnostic odds ratio, SROC summary receiver operating characteristic, SE standard error