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Table 4. Univariate analyses of patients with or without 30% pain relief by mirogabalin

From: Short-term outcomes of mirogabalin in patients with peripheral neuropathic pain: a retrospective study

Variables

< 30% pain relief

(n= 50)

≥ 30% pain relief

(n= 113)

pvalue

Age (years)

72.9 ± 11.9 (45–88)

71.3 ± 13.0 (30–94)

0.46a

Sex, female/male

30/20

82/31

0.11b

Diagnosis

  

0.75b

 LCS

35

83

 CSM

11

17

 LDH

2

7

 CTS

2

6

 Others

0

1

BMI (kg/m2)

22.7 ± 4.2 (18–33)

23.0 ± 3.8 (19–31)

0.79a

DM

4

11

0.72b

NeP score (points)

7.4 ± 2.1 (6–12)

6.6 ± 1.4 (6–12)

0.0047a

Primary doze (mg)

3.1 ± 1.5 (5–10)

3.1 ± 1.1 (5–10)

0.97a

Max dose (mg)

6.6 ± 3.8 (5–30)

6.4 ± 3.8 (5–30)

0.76a

Adverse events

24 (48%)

42 (37.2%)

0.13b

 Somnolence

17 (34%)

27 (23.9%)

 

 Dizziness

6 (12%)

10 (8.8%)

 Edema

2 (4%)

5 (4.4%)

 Weight gain

1 (2%)

0 (0%)

  1. Data are expressed as the mean ± standard deviation (range) or n (%).
  2. LCS lumbar canal stenosis, CSM cervical spondylotic myelopathy, LDH lumbar disc herniation, CTS carpal tunnel syndrome, BMI body mass index, DM diabetes mellitus, NeP neuropathic pain
  3. a Student’s t-test
  4. b Chi-squared test