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Fig. 7 | Journal of Orthopaedic Surgery and Research

Fig. 7

From: In vitro analysis of the effect of Flightless I on murine tenocyte cellular functions

Fig. 7

FliiTg/Tg tenocytes show decreased collagen type I expression in response to wounding in vitro. Confluent tenocytes were scratch-wounded and stained for collagen type I expression at 3, 6, 12, and 24 h post-wounding. a–l Representative images showing collagen type I expression in Flii+/−, WT, and FliiTg/Tg tenocytes at 3, 6, 12, and 24 h post-wounding. Magnification × 10. Scale bar = 100 μM. Collagen type I represented by white arrows. m Graphical representation of collagen type I expression in tenocytes. FliiTg/Tg tenocytes show a later peak of collagen type I release than Flii+/− cells. *p ≤ 0.05 between Flii+/− and FliiTg/Tg. ^p ≤ 0.05 between Flii+/− and WT. +p ≤ 0.05 between FliiTg/Tg and WT. Data represented as mean ± SEM. n = 6

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