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Table 4 Significantly upregulated genes in both bone and kidney (GZZSZTW vs. Blank)

From: Deciphering the potential pharmaceutical mechanism of Guzhi Zengsheng Zhitongwan on rat bone and kidney based on the “kidney governing bone” theory

Gene nameBoneKidney
Blank (FPKM)GZZSZTW (FPKM)log2 fold change (GZZSZTW/Blank)p valueBlank (FPKM)GZZSZTW (FPKM)log2 fold change (GZZSZTW/Blank)p value
Cation channel sperm-associated protein 2 (Catsper2)0.512.632.372.02E−061.683.961.242.67E−05
Period circadian protein homolog 3 (Per3)1.394.171.583.29E−052.196.661.604.74E−18
Schlafen family member 12-like (Slfn12l)38.51264.682.7801.292.621.024.83E−06
Minor histocompatibility protein HA-1 (Hmha1)26.1674.341.514.20E−1381.402.931.079.10E−06
Transcription factor jun-B (Junb)13.6536.861.434.01E−3018.2451.841.513.68E−60
Cadherin-23 (Cdh23)0.190.832.131.45E−080.090.712.989.60E−14
Fetuin-B (Fetub)0.934.992.421.73E−072.637.661.546.98E−10
Protocadherin gamma-A11 (Pcdhga11)0.010.485.583.61E−050.100.702.816.73E−06
Protein BANP (Banp)4.5213.571.591.40E−183.919.661.305.39E−15
Protein phosphatase 1 regulatory subunit 1A (Ppp1r1a)0.462.522.459.74E−05174.26401.401.201.34E−274
Beta-enolase (Eno3)5.7232.642.514.42E−441.824.821.411.12E−04
Ankyrin repeat domain-containing protein 13D (Ankrd13d)1.403.551.342.71E−040.431.711.991.22E−04
Autophagy-related protein 16-2 (Atg16l2)4.139.461.203.16E−081.052.711.371.85E−04
B cell lymphoma 6 protein homolog (Bcl6)3.508.671.319.91E−133.066.381.061.39E−09
Proto-oncogene c-Fos (Fos)5.4712.821.232.31E−120.7510.373.797.87E−31