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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Knockdown of long non-coding RNA PVT1 induces apoptosis of fibroblast-like synoviocytes through modulating miR-543-dependent SCUBE2 in rheumatoid arthritis

Fig. 1

High expression of PVT1 is identified in synovial tissues of RA patients and rats. a The heatmap of top 30 differentially expressed lncRNAs in synovial tissues of 3 healthy people and 3 patients with RA analyzed by human lncRNA expression array V3.0 (AS-LNC-H-V4.0, Arraystar Inc.). b Observation of the hind paw of control and RA rats at the 2nd, 3rd, and 4th week after modeling. c A chart of the increase of paw swelling (%). d PVT1 expression in synovial tissues of RA and control rats by RT-qPCR. *p < 0.05 vs. the control rats; n = 7 for each group. All data were measurement data and presented as mean ± standard derivation; ANOVA was used for the comparison among multi-groups

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X