Variable | Hazard ratio | 95% CI | P value | Reference/remarks |
---|---|---|---|---|
Age of surgery | 1.008 | 0.992–1.024 | 0.333 | For every year increase in age |
ASA status (2:3) | 1.506 | 1.004–2.257 | 0.480 | ASA 3 against ASA 2 |
CCI (0:≥1) | 1.241 | 0.822–1.873 | 0.305 | No comorbidities against CCI ≥ 1 |
Albumin | 1.100 | 1.062–1.139 | < 0.001 | For every 1 g/L decrease |
Haemoglobin (Hb) | 1.159 | 1.028–1.307 | 0.016 | For every 1 g/dL decrease |
Site of primary tumour | Â | Â | Â | Lung as reference |
Breast | 0.394 | 0.223–0.697 | 0.001 |  |
Prostate | 0.426 | 0.192–0.945 | 0.036 |  |
Renal | 0.758 | 0.356–1.615 | 0.473 |  |
Others | 1.128 | 0.667–1.907 | 0.653 |  |
Presence of visceral metastases (yes:no) | 1.675 | 1.110–2.535 | 0.014 | Visceral metastasis present against absent |
Presence of spinal metastases (yes:no) | 1.071 | 0.678–1.689 | 0.769 | Spinal metastasis present against absent |
Time from diagnosis of cancer to incidence of pathological fracture | 0.995 | 0.992–0.999 | 0.016 | For every month between diagnosis of cancer to fracture |
Pathology (actual fracture:impending fracture) | 1.185 | 0.791–1.774 | 0.411 | Treatment of actual fracture against treatment of impending fracture |
Site of fracture/lesion | Â | Â | Â | Shaft/distal femur as reference |
Neck of femur | 0.722 | 0.427–1.221 | 0.224 |  |
Intertrochanteric/subtrochanteric | 0.833 | 0.511–1.360 | 0.465 | 5 bilateral cases excluded |
Type of surgical procedure (bipolar hemiarthroplasty:intramedullary nail) | 0.854 | 0.521–1.401 | 0.533 | Bipolar against nail 15 cases excluded (10 plate and screws and 5 bilateral) |