Skip to main content

Table 1 Summary characteristics of studies and participants

From: The relationship between serum vitamin D and fracture risk in the elderly: a meta-analysis

Name

Year

Study type

TF/HF/N

Sex

Age

Country

Period

Follow-up (year)

Adjustment

van Schoor et al

2008

Cohort

115\0\1311

Both

≥ 65

Netherland

1992–1993

6

Age, sex, season, education, BMI, number of chronic, diseases, creatinine level, cognition, smoking, and alcohol use

Chan et al

2011

Cohort

72\24\712

Men

≥ 65

China

2001–2003

4

Age, BMI, education, PASE, DQI, smoking status, and alcohol use

Nakamura et al

2011

Cohort

51\0\4250

Women

≥ 69

Japan

2009

6

Age, BMI, BMD, medication of osteoporosis and PA

Barbour et al

2012

Cohort

331\84\2614

Both

≥ 70

USA

1997–1998

6.4

Age, gender, race, education level, season of blood draw, BMI, current drinking, fracture after age 45 and clinical comorbidity index

Looker et al

2013

Cohort

525\287\4749

Both

≥ 65

USA

2000–2004

7

Age, sex, race/ethnicity, and survey

Bleicher et al

2013

Cohort

123\0\1662

Men

70–79

Australia

2005–2007

4.3

Age, country of birth, BMI, PA, season of blood draw, previous fracture after age 50 years, calcium and vitamin D supplement, and BMD

Tanaka et al

2014

Cohort

382\42\1470

Women

63.7 ± 10.7

Japan

2003

7.2

BMD, age, weight, diabetes mellitus, PTH, eGFR, prior fracture, back pain, bisphosphonates, SERM, active vitamin D

Swanson et al

2015

Case cohort

432\81\1000

Men

74.6 ± 6.2

USA

2000–2002

4.5

Age, race, site, season, PA, height, weight, baseline hip BMD,1,25(OH)2D measure, and incident falls in the first year of follow-up

Cauley et al

2010

Case cohort

436\81\1929

Men

≥ 65

USA

2000–2002

5.3

Age, race, clinic, season of blood draw, physical activity, weight, and height

Bolland et al

2009

Cohort

385\22\1471

Women

Mean 74

New Zealand

1998–2003

5

Treatment allocation (calcium or placebo) and baseline age, body weight, and smoking status

Garnero et al

2007

Cohort

134\0\669

Women

Mean62.2

France

1992–1993

11.2

Age, prevalent fracture, and PA

deBoer et al

2012

Cohort

0\137\1621

Both

≥ 65

USA

1992–2006

11

Age, sex, clinical site, smoking, body mass index, and physical activity.

Looker et al

2008

Cohort

0\156\1917

Both

≥ 65

USA

1988–1994

6.7

Age, sex, femoral neck BMD, BMI, previous fracture, dietary calcium, kilocalories, and weight loss from maximum

Steingrimsdottir

et al

2014

Cohort

0\261\5471

Both

≥ 66

Iceland

2002–2006

5.4

Age, sex, body mass index, height, smoking, alcohol intake and season, physical activity

Cummings et al

2013

Cohort

271\133\878

Women

≥ 65

USA

1986–1988

5.9

Age and weight

Robinson et al

2011

Cohort

0\242\2249

Both

≥ 65

USA

1989–2009

13

Age, race, sex, clinic site, a season, education, smoking status (never smoker, former smoker, or current, smoker), alcohol use (any vs. none), diabetes status (normal, impaired fasting glucose, or diabetes), body mass index, self-reported health status, physical activity level, oral steroid use, estrogen use, thiamine and loop diuretic use, serum cystatin C level, and calcium supplement use

Holvik et al

2013

Case cohort

0\1175\2526

Both

≥ 65

Norway

1994–2001

10.7

Age, gender, study center, BMI, and month of blood sample

Buchebner et al

2014

Cohort

349\130\1044

Women

75

Sweden

1995–1999

13.1

smoking, bisphosphonate use, and physical activity level

Kauppi et al

2013

Cohort

0\95\3305

Both

62.9

Finland

2000–2001

8.4

Gender, age, height, weight, BMI, QU, alcohol consumption, smoking, and PA

Ginsberg et al

2018

Case cohort

0\289\890

Both

Mean78

USA

1989–2006

8.4

Age, sex, race, season of measurements, site of measurement and BMIeGFR, serum calcium, phosphate and FGF-23

  1. TF total fractures, HF hip fractures, N cases