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Table 2 Univariate Cox regression analysis for evaluating the influence of Regional dissection on survival of patients with primary metastatic osteosarcoma in SEER database

From: A population-based propensity-matched study of regional dissections in patients with metastatic osteosarcoma

CharacteristicsOSCSS
HR (95% CI)PHR (95% CI)P
Treatment    
 Non-regional dissectionReference Reference 
 Regional dissection0.34 (0.26-0.44)<0.0010.33 (0.25-0.43)<0.001
Sex    
 FemaleReference Reference 
 Male1.00 (0.78-1.29)0.9801.03 (0.79-1.33)0.851
Race    
 WhiteReference Reference 
 Black0.77 (0.53-1.12)0.1700.72 (0.48-1.08)0.114
 Other race1.29 (0.82-2.02)0.2681.39 (0.89-2.18)0.152
Age    
 <18Reference Reference 
 18-652.16 (1.66-2.80)<0.0012.14 (1.63-2.81)<0.001
 >=654.11 (2.65-6.38)<0.0014.48 (2.88-6.98)<0.001
Grade    
 Well/moderateReference Reference 
 Poorly/undifferentiated0.53 (0.28-1.00)0.0490.48 (0.25-0.91)0.024
 Unknown0.65 (0.34-1.27)0.2120.61 (0.31-1.19)0.148
T Stage    
 T1Reference Reference 
 T20.97 (0.68-1.39)0.8840.97 (0.67-1.39)0.855
 T31.48 (0.84-2.59)0.1711.56 (0.88-2.75)0.121
 Tx1.26 (0.84-1.88)0.2691.13 (0.74-1.72)0.584
Chemotherapy    
 No/unknownReference Reference 
 Yes0.53 (0.34-0.83)0.0050.49 (0.31-0.76)0.001
Radiation    
 No/unknownReference Reference 
 Yes2.20 (1.62-2.99)<0.0012.20 (1.60-3.03)<0.001
Location    
 ExtremityReference Reference 
 Other2.53 (1.89-3.41)<0.0012.50 (1.84-3.41)<0.001
  1. Abbreviation: SEER=Surveillance, Epidemiology and End Results; OS=Overall survival; CSS=Cause-specific survival