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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis

Fig. 6

Effect of Cadherin-11 antibody on cartilage damage score in CIOA mice. Representative photomicrographs of Safranin O/Green staining of knee joints in CIOA mice (a). Cadherin-11 antibody showed significant inhibitory effect on cartilage damage score in MTP (b, p < 0.05), MFC (c, p < 0.05), LTP (d, p < 0.05), LFC (e, p < 0.05), and summed cartilage damage score (f, p < 0.05) (n = 6, 9, and 9 per group respectively; data presented as mean ± SEM; Kruskal–Wallis test followed by Mann–Whitney U test, *p < 0.05, **p < 0.01, ***p < 0.001)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X