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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis

Fig. 4

Effect of LY294002 on OARSI cartilage score in CIOA mice. Representative photomicrographs of Safranin O/Green staining of knee joints in l CIOA mice (a). LY294002 showed no significantly inhibitory effect on cartilage damage score in MTP (b, p > 0.05), MFC (c, p > 0.05), LTP (d, p > 0.05), LFC (e, p > 0.05), and summed cartilage damage score (f, p > 0.05) (n = 6 per group respectively; data are presented as mean ± SEM; Kruskal–Wallis test followed by Mann–Whitney U test, *p < 0.05, **p < 0.01, ***p < 0.001)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X