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Table 1 Preoperative patient characteristics

From: Linezolid versus daptomycin treatment for periprosthetic joint infections: a retrospective cohort study

Characteristics

Group L

Group D

P value

Number of joints

39

43

Ā 

Mean age at surgery, years (range)

75 (37ā€“104)

70 (36ā€“88)

0.067a

Gender, male to female

12:27

20:23

0.144b

Mean follow-up period, months (range)

45 (1ā€“96)

22 (1ā€“48)

<ā€‰0.001 c

Number of patients administered other antibiotics before this therapy

32

25

0.019 b

Mean dose, mg/kg/day (range)

22.3 (13.3ā€“40.0)

6.0 (3.1ā€“10.6)

<ā€‰0.001 c

Mean duration, day (range)

17 (5ā€“50)

25 (1ā€“106)

0.193c

Number of patients administered rifampicin

2

35

0.019 b

Surgical intervention during this therapy, number

ā€ƒNone

18

12

0.087b

ā€ƒOnly debridement

7

12

0.286b

ā€ƒDebridement and implant removal

0

2

0.272d

ā€ƒOne-stage revision

0

5

0.035 d

ā€ƒTwo-stage revision

13

6

0.038 b

ā€ƒShift to another antibiotic after identification

1

6

0.071d

  1. aStudentā€™s t test
  2. bPearsonā€™s chi-squared test
  3. cMann-Whitney U test
  4. dFisherā€™s exact test