Characteristics | Group L | Group D | P value |
---|---|---|---|
Number of joints | 39 | 43 | Ā |
Mean age at surgery, years (range) | 75 (37ā104) | 70 (36ā88) | 0.067a |
Gender, male to female | 12:27 | 20:23 | 0.144b |
Mean follow-up period, months (range) | 45 (1ā96) | 22 (1ā48) | <ā0.001 c |
Number of patients administered other antibiotics before this therapy | 32 | 25 | 0.019 b |
Mean dose, mg/kg/day (range) | 22.3 (13.3ā40.0) | 6.0 (3.1ā10.6) | <ā0.001 c |
Mean duration, day (range) | 17 (5ā50) | 25 (1ā106) | 0.193c |
Number of patients administered rifampicin | 2 | 35 | 0.019 b |
Surgical intervention during this therapy, number | |||
āNone | 18 | 12 | 0.087b |
āOnly debridement | 7 | 12 | 0.286b |
āDebridement and implant removal | 0 | 2 | 0.272d |
āOne-stage revision | 0 | 5 | 0.035 d |
āTwo-stage revision | 13 | 6 | 0.038 b |
āShift to another antibiotic after identification | 1 | 6 | 0.071d |