Fig. 2From: Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in ratsa EMO induces protein-related changes in ER stress pathway in a dose-dependent manner, including GRP78, P-PERK, PERK, P-eIF2a, eIF2a, and CHOP, which were detected by western blot following the treatment of 0, 5, 10, and 20 μg/ml EMO for 24 h. GAPDH was set as a loading control. b The histogram shows the band intensity ratio of P-PERK/PERK and P-eIF2a/eIF2a. The result was repeated for three times. *P < 0.05 versus the control group. c The expression of GRP78 and CHOP relative to GAPDH was shown as a histogram. The result was repeated for three times. *P < 0.05 versus the control groupBack to article page