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Table 3 Clinicopathological factors associated with overall survival based on univariate Cox proportional regression analysis

From: Transferrin receptor-1 and VEGF are prognostic factors for osteosarcoma

Characteristics Overall survival P
HR 95% CI
Sex Female 25 1   0.837
  Male 28 1.064 0.590–1.919
Age ≥ 20 years 18 1   0.777
  < 20 years 35 1.093 0.591–2.022
Tumor size < 5 cm 27 1   0.940
  ≥ 5 cm 26 1.024 0.556–1.884
Histologic grade* I 15 1   0.412
  II 25 1.267 0.634–2.534 0.503
  III 13 1.738 0.771–3.917 0.183
Distant metastasis* Yes 23 1   < 0.001
  No 30 0.161 0.073–0.356
Enneking staging* I 12 1   < 0.001
  II 19 8.605 2.942–25.169
  III 22 26.039 7.679–88.293
TfR1* Low 11 1   < 0.001
  Moderate 19 0.158 0.063–0.398
  High 23 0.300 0.143–0.629
VEGF* Low 10 1   0.021
  Moderate 19 0.114 0.043–0.303
  High 24 0.422 0.202–0.880
  1. HR, hazard ratio; 95% CI, 95% confidence interval. *P < 0.05